Sentence examples for difficult to confer from inspiring English sources
Current screening platforms, however, rely on measuring protein interactions in rather artificial systems, rendering the results difficult to confer on the in vivo situation.
These results also illustrate how it is much more difficult to confer a specific functional activity of a protein to a closely related isoform than to disrupt this activity.
Historically, neutralizing antibodies were presumed to be genotype-specific rendering it very difficult to confer global protection.
Although we were unable to achieve rescue of fast neurotransmitter release in synaptotagmin-1 KO neurons with the Syt1/7 chimeras, our experiments with multiple mutants underscore how difficult it is to confer a specific activity to a protein isoform even when the starting point is a closely related isoform.
The level of MDR proteins is very low and therefore difficult to detect, but may be sufficient to confer low-level, but clinically relevant, resistance to some cytotoxic agents, especially vincristine.
For some pests, however, it may sometimes prove difficult to select for levels of resistance high enough to confer survival on Bt crops.
The prevalence of the more complex type I venoms in rattlesnakes [ 29] is difficult to reconcile with the advantages type II venoms appear to confer.
Beside their aggressive growth particularly the loss of capacity to uptake iodine makes both dedifferentiated and anaplastic thyroid carcinomas difficult to treat, and confer the poor patient prognosis.
This lack of sensitivity also makes describing what participants are doing difficult, limiting discussion about what type, intensity, and frequency are minimal and optimal to confer benefit.
Resistance mutations due to increased expression of cellular machinery tend to confer resistance to multiple antibiotics, especially for efflux pumps, and can be difficult to identify (Suzuki et al. 2014).
Judge Irenas also found that Mr. Zeitz failed to confer closely enough with Mr. Marshall -- who the lawyer described as an unusually difficult client -- about the death-penalty phase of the trial.
