Sentence examples for difficult to clearly establish from inspiring English sources

Therefore, it is sometimes rather difficult to clearly establish which atoms of the ligands are bound to the metal and to decide which bond order scheme suits a given compound the best.

However, it is difficult to clearly establish a direct relationship between their structure and antiproliferative activity, as substantial structural changes might not only affect their anticancer activity but also tightly control their activation site(s) and/or their biological target(s).

Moreover, the impact on antioxidant status was not examined, so it is difficult to clearly establish the relationship between these two conditions.

Another potential explanation is that Atg17 and Atg1 are subunits of the same complex and appear to function together during autophagy induction, which makes it difficult to clearly establish their hierarchical relationship.

The recordings were played in court, with many difficult to clearly hear.

This makes it difficult to clearly define axial and equatorial positions.

Hence, it might sometimes be difficult to clearly distinguish between "assay promiscuity" and true target promiscuity.

In cases in which differential diagnosis is difficult to establish, histopathological examination establishes the final diagnosis.

Direct-to-consumer marketing and the widely available hype from the media and Internet websites make it difficult to do the randomized controlled trials that would clearly establish one type of prosthesis or procedure to be superior.

"We do discipline students who fail to follow clearly established policies.

"Those kinds of relationships are very, very difficult to establish, and sometimes it takes years to establish," Mr. Baker said.