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This paper develops a protocol that eliminates the need to calculate required sample size; sample size is difficult to calculate in advance because HPV's true type-specific prevalence is imperfectly known.
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It is very difficult to calculate in finite terms but it is that order of magnitude," Mr Rose said.
The FAO's Abdolreza Abbassian argues that increasing links between farming and other parts of the economy are making it more difficult for farmers to calculate in advance the profitability of any one crop, so the area they plant is tending to fluctuate more sharply from year to year.
It is difficult to calculate the extent of the adjustment effort in advance because details concerning the adaptation do not fully emerge until the actual adaptation is in progress.
An exact figure is difficult to calculate because of vagaries in the way fund-raising numbers are reported.
Dr. Saudek cautioned, however, that it can be difficult to calculate the amount of carbohydrates in some foods.
The number of deaths in the US wars in Iraq and Afghanistan are difficult to calculate since the US only counts US deaths.
Contractors expect steel prices to rise in coming months, which made it difficult to calculate final bids.
George Best Airport in Belfast would be another candidate, and while it's difficult to calculate a current value it was sold to ABN Amro in 2008 for £132.5m.
It is difficult to calculate the exact number of young homeless people in the UK.
The risk of crisis in each situation is difficult to calculate.
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