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"Those children who were unfortunate enough to grow up in poverty, without a stable family background, without access to those connections, find it increasingly difficult to benefit from education".
Patients with prior exposure to multiple anti-TNFs are likely to have advanced RA and may find it difficult to benefit from any therapy; furthermore, previous studies have shown that no or low prior exposure to biologic agents is associated with longer drug survival in patients receiving tocilizumab or anti-TNFs [ 14, 23, 30].
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Because of the large capital investments it has been difficult for smaller local companies to benefit from privatization.
GDT protocols are complex and it is difficult to attribute benefit to specific components of each strategy.
Commercially and practically it is difficult to demonstrate benefit in such chronic pain populations and very large studies are needed to show superiority.
It's difficult to say what benefit the treatment finally had.
[2013 survey] "Certain services and rotations make it difficult to learn and benefit from academic Tuesday".
[2014 survey] Fellows' comments reflected barriers and opportunities for further improvement: "Certain services and rotations make it difficult to learn and benefit from academic Tuesday".
But if cost controls do not produce the expected savings, Congress is likely to find it difficult to preserve benefits without increasing taxes.
Nonetheless, CMMI-DEV and MPS.BR assessments concentrate on the lower maturity levels, making more difficult to obtain benefits with implementation of higher maturity level best practices.
First, it is difficult to measure benefits of engaging citizens.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com