Sentence examples for difficult to be validated from inspiring English sources

This initial "cutoff" criterion was chosen based on our experiences (Syed et al. 2005; Tam et al. 2008); changes in gene expression < 1.5-fold are difficult to be validated by real-time RT-PCR.

The peculiarities of NCL have been discussed in the paper, especially those that make it particularly difficult or impractical to be validated by XML Schema or DTD, standards commonly used with other XML-based languages employed in iTV, such as SMIL, XHTML and BML.

The accuracy of EBV derived from large numbers of markers for within-breed selection is difficult to evaluate analytically and must be validated by correlating predictions to phenotype in the target population (usually the generation following training).

More difficult to validate are organ doses for which no assay exists, for example, the dose received from intakes of iodine-131.

In addition, after trying to validate the gene expression pattern differences measured by the microarray between 4dpi or 7dpi and 0dpi, it became clear that the 7dpi-0dpi dataset was difficult to validate, as was also seen earlier by Arceo et al. [ 22].

Becerra's artistic journey hasn't been easy; it was difficult to "feel validated or encouraged" as an artist growing up in a working class, Latino family.

Many claim to offer improvements over older designs but such assertions are difficult to validate when there is no consensus as to how such implants should be tested in vitro or even if such testing is necessary.

Though the 'moisture sensing depth' is difficult to validate experimentally, it is consistent with experimental results [13].

Generally, computational methods identify a larger number of potential drug targets which could be difficult to experimentally validate all of the targets due to time and cost constraints.

These temporary increases in morbidity in the models would be difficult to validate in the field because they are small relative to year-to-year variability, and studies of such phenomena are unlikely to involve long follow-up periods and matched controls.

It is common that low expressing genes in microarrays are usually difficult to validate and can often be filtered out from the analysis.