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With these machining conditions, because of the glass-like property of the PMMA thin film and a relatively small applied load by the AFM tip, the chains between the polymer molecules cannot be broken and plastic deformation is difficult to be generated to modify the sample surface by one cycle of the press operation.
The reason is that, the population of double, triple or quadruple mutants might be technically difficult to be generated [ 9]. (iv) For four genotypes (i.e., RowID 5, 21, 29, and 45) are called unstable patterns, because genetic condition will lead to an unstable fate pattern as shown in Table 9.
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In general it is very difficult to ascertain whether biomarker proteins are generated by the cancer itself or by secondary effects, such as immune response.
For this reason, it has remained difficult to experimentally demonstrate how cognitive ERPs are generated.
What has been difficult to generate is a genetic model system that can test this independent of other activities.
Furthermore and importantly, we will see below that from a purely molecular-biological perspective, the tuning of NBDM may not be difficult to generate mechanistically and is not likely to entail problematic trade offs with the optimization of other functions.
The Tories say this is contradicted by an official Treasury analysis that found such restrictions would "be difficult to frame, generate market uncertainty on London's Eurobond market, and could be structured around, so providing negligible Exchequer yield".
In kiwifruit, artificially generated mutations are difficult to generate and screen and genetic transformation is a difficult and lengthy process.
The cross-section of the maple seed was difficult to generate and would not be reliable at high wind speeds.
It is difficult to standardize data generated from different genotyping platforms, and comparison of data is further complicated, because the same allele may be binned differently.
Although, fortunately, these mutations would be difficult to generate outside the laboratory, they were useful in supporting the novel mechanism of action, since these genetic alterations did not affect the action of other ribosomal drugs.
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CEO of Professional Science Editing for Scientists @ prosciediting.com