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3 Environmental factors that contribute to the development of malignant gliomas are notoriously difficult to ascertain with confidence.
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The microstructural origin of this behavior is difficult to ascertain with macroscopic observations.
DNA damage is difficult to ascertain with certainty.
Exposure to an environmental species which naturally sensitises individuals to Ag85 makes a persistent vaccine effect more difficult to ascertain with increasing age.
It is difficult to ascertain with the available information the proximity of the AVM to the optic nerve and its blood supply.
In some cases, it was difficult to ascertain with certainty which recommendations in each report were based on research evidence, which on expert opinion and which on experience.
Hence, we were unable to ascertain with confidence whether any particular A/H1N1pdm virus genotype trended with A/H1N1pdm infection severity in our nationwide survey.
This makes it difficult to ascertain who to trust in times of crisis.
This is difficult to ascertain among black subjects with HbA1c ≥ 6.5% (48 mmol/mol), whose HbA1c was 7.4 ± 1.5% (see Table 1 in Selvin et al. [ 1]).
It is also difficult to ascertain the financial costs associated with BFHI implementation and accreditation and, to date, there has not been a cost benefit analysis of BFHI.
Rif losses have been much more difficult to ascertain; one estimate calculated 30,000 casualties, with 10,000 deaths.
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