Sentence examples for difficult to administer the from inspiring English sources

Usually in the elderly it is difficult to administer the same chemotherapy administered to younger patients because elderly patients tolerate chemotherapy poorly.

However, it is difficult to administer the lipids deep into the interface in healthy skin using conventional formulations such as ointments and creams.

While this therapy has been difficult to administer in the past due to technical challenges of safely delivering heat, improvement in heat delivery technology for urologic malignancies, especially for prostate and bladder cancers, has led to a reemergence of hyperthermia.

Although this study demonstrates that both FCR and BR are highly active regimens, significant toxicity occurs even in these younger fit patients, making both regimens difficult to administer to the older, unfit patient population.

However, many polymers are difficult to administer or lack the structural integrity to restore LV function.

Dr. Kimmett testified that it was "very difficult" to administer plasma on the train, and that two men died between Jasper and Edson.

These 'individualized' measures, although sometimes difficult to administer and interpret, put the patient at the centre rather than at the periphery of assessing the effectiveness of treatment interventions.

State laws make it difficult to administer simple treatments in the home.

Questionnaires, even verbally completed, were unsuccessful and difficult to administer as participants found the questionnaire structure and design difficult to follow and did not perceive any benefit to completing the questionnaires.

"The problem with a targeted system is it is difficult to administer and doesn't have the same buy-in as a scheme that offers support as widely as possible".

The authors already noted that inhalation therapy may be difficult to administer in aged patients – stressing the age itself as an important factor for appropriate inhalation.