Sentence examples for difficult to administer and from inspiring English sources

Before then, drug treatments for depression were difficult to administer and sometimes dangerous.

The cap-and-trade system is not working because it is expensive and difficult to administer and is applied only to those polluters that can be identified.

But the vaccine is expensive to make and difficult to administer, and it is not yet clear how long the protection lasts.

Dr. Ethel Siris, a professor of clinical medicine and director of the Osteoporosis Center at Columbia University Medical Center, said that Forteo was a very effective drug but difficult to administer, and that this kind of technology could prove useful.

Although there are drugs to stanch the loss of bone and the debilitating fractures that often result, the remedies are costly, difficult to administer and sometimes have side effects that can be worse than the disease they are meant to counter.

However, large-scale surveys and long questionnaires can be biased, unreliable and difficult to administer and analyse.

While the standard approach to utility elicitation is the standard gamble, we chose to use alternate approaches to estimate utility, namely visual analogue scale (VAS), willingness to pay (WTP) and time trade off (TTO), as the standard gamble is more complex and difficult to administer (Morimoto and Fukui, 2002; Ross et al, 2003).

Eflornithine is effective only against T. brucei gambiense infections and is difficult to administer, requiring hospitalization and intravenous infusions every 6 h for 2 weeks (7), although a recently introduced combination therapy of nifurtimox and eflornithine (NECT) has reduced the treatment burden (13).

The original measure is made up of 37 items, but is considered long and difficult to administer in clinical settings and population-based studies [ 12- 14].

These combinatorial therapies are difficult to administer for both patient and caregiver and often result in tolerability issues.

Questionnaires, even verbally completed, were unsuccessful and difficult to administer as participants found the questionnaire structure and design difficult to follow and did not perceive any benefit to completing the questionnaires.