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The percentage of shares outstanding that they have to short to make it worthwhile makes it difficult to accumulate a position and increases the risk of being caught in a short squeeze.
The development of a growth reference specific for preterm and VLBW infants is, however, difficult as many of these infants have significant morbidity in the neonatal period and infancy making it difficult to accumulate a large, representative sample of "healthy" VLBW infants.
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Books started to accumulate, "A" through "Z," in my room.
The case numbers were difficult to accumulate in a short time because most blunt chest traumas could be treated with non-surgical methods and only about 10% of blunt chest injuries will evolve to retained pleural collections where surgical interventions should be arranged.
In the regions of extensively hydrated plate boundaries that produce abundant clay minerals such as chlorite, a large elastic strain is difficult to accumulate and does not generate large thrust earthquakes, whereas the regions escaped from the hydration reactions could result in a strong mechanical coupling that acts as a seismic asperity.
For example, a link between social deprivation and poorer quality of care as judged by QOF scores might arise because GPs in more deprived areas have larger, more unmanageable lists, or because they have a higher turnover of patients making it difficult to accumulate sufficient clinical successes.
But killing large numbers of people with chemical weapons would require a big stockpile of deadly substances which would be difficult to accumulate without attracting suspicion.
Avoid using penny stocks as a strategy for your retirement account, as it is very difficult to accumulate consistent wealth from penny stocks.
Entrepreneurs were forced to self-finance, but negative real interest rates made it difficult to accumulate the necessary savings.
It is relatively difficult to accumulate the savings needed to pay cash for housing, and so homeownership will be less common than renting unless borrowing to purchase is made cheap and easy.Unfortunately, the introduction of leverage makes things messy.
The change of organizational teams makes it difficult to accumulate crowd management experience over many events.
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CEO of Professional Science Editing for Scientists @ prosciediting.com