(Crown Estate profits flow into the Treasury, which faces a fiscal crunch).Building on dry land is difficult too: suitable sites are rare, and Britain's planning system hands obstreperous local residents a lot of power.
Diagnosis of Alzheimer's disease in patients is still difficult, and suitable biomarkers are sought.
As access to large numbers of fresh breast tissue to perform such studies is difficult, a suitable surrogate test tissue must be identified for future studies.
This simple concept has not been adopted in practice, perhaps because early experience suggested that a change of chemotherapy should be made anyway (Smith et al, 2002) and perhaps because response monitoring is difficult and suitable criteria for a satisfactory response after the first course(s) are not available.
Investigating the effects of the synergy between air pollution and high temperature on mortality, although desirable, is difficult, because a suitable study site is not easily available.
The Department for Environment, Food and Rural Affairs (Defra) argues that it is difficult to identify suitable habitats for the porpoises, but this is disputed by conservationists.
Thereafter, he found it difficult to find suitable employment and sometimes was forced to rely on family and friends for financial support.
But while well-financed public projects have taken over and renovated old industrial sites, the city's contemporary artists have often had a more difficult time finding suitable accommodation.
Neil Unitt, managing director of Farmplan, which turns over about £5m a year selling it to farmers, says that the peculiarities of the business and British government legislation make it difficult to import suitable software.His firm began making stock- and crop-management programmes about 25 years ago.
The British lender said it had walked away from the acquisition because of weakness in the local economy that would make it difficult to generate suitable returns, according to Peter Marks, the outgoing chief executive of the bank's parent, the Co-operative Group, which operates a range of businesses including supermarkets and funeral homes.
