Sentence examples for difficult sample preparation from inspiring English sources

The limitation of this technique, however, stems from the difficult sample preparation, which may change the morphology of the cells [31].

The present findings provide fundamental insight into the reliability analysis on the metallic nanowire mesh hindered by difficult sample preparation and experimental measurement, which will be helpful to develop ideal metallic nanowire mesh-based TCE with considerable reliability.

The simplicity and accessibility of SPMA can overcome bottlenecks due to difficult sample preparation and handling in urinary proteomics.

Traditional approaches, such as HPLC and MS, while useful, have difficult sample preparation and require high amounts of input DNA (micrograms) [ 24] thus severely limiting its adoption in routine diagnostics.

In this case, there is no simple relationship between the amounts of retained analytes and their concentrations in the sample what makes quantitative analysis more difficult compared to sample preparation based on partitioning mechanism.

This is especially true for breast tissues which contain a high content of fat, which makes sample preparation difficult.

These sources are difficult to exclude in sample preparation; the rough microtopography of many macrofossil surfaces, as well as the frequent occurrence of tears or fissures, provide opportunity for materials from the surrounding sediment matrix to attach or infiltrate.

These results indicate that the down field peak is assigned to the Cys S-13CH3 carbons in the domain with the ordered structure where the disulfide bond is relatively difficult to reduce during the sample preparation.

Sample preparation is difficult for SEM imaging and it cannot be used for studying the dynamics of myelin figures.

The consistent behavior of figure of merit in both meshes indicates that the known Z and the melting behavior of the Ag microwire mesh can be used to predict the melting behavior of the nanowire mesh even with different materials (e.g., Ag nanowire mesh, Al nanowire mesh), which is hindered by the cost of sample preparation and the difficult control of ultra-low current stressing in experiments.

Validation of gene classifiers with independent samples from which they were developed from is a major challenge for microarray studies, especially those with clinical implications, and combining multiple datasets can be difficult due to different patient populations, sample preparation and microarray platforms.