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Harkin says he has been finding it increasingly difficult in dealing with his bank, and that he is seeing other avenues of funding being cut-off.
While it is admittedly difficult, in dealing with a human being, rather than a laboratory animal, to "prove" that Cause A produces Effect B, plain common sense suggests that the relation between a soaring rate of liver disease and the prevalence of liver poisons in the environment is no coincidence.
But these operators have difficult in dealing with large scale problems because of the high computational cost.
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Stigma is perhaps the most difficult challenge in dealing with H.I.V./AIDS in Afghanistan.
It's arguably the most difficult challenge in dealing with climate change: how to reduce emissions from food production while still producing enough to feed a global population projected to reach 9 billion by the middle of this century.
"Clearly, D.O.T. will be facing some difficult issues in dealing with new requirements that will impact the current work force of security screeners," he said, including the new mandate that all screeners be United States citizens.
"I agree, this is the thorniest and most difficult issue in dealing with illegal immigration," conceded Bachmann.
When the inquiry reports, one year after it started, Cameron will be faced with difficult choices in dealing with any recommendations on press regulation.
He faced a difficult challenge, however, in dealing with Sulley's sheer mass; traditionally, animators conveyed a figure's heaviness by giving it a slower, more belabored movement, but Kahrs was concerned that such an approach to a central character would give the film a sluggish feel.
The move was difficult, not least in dealing with the complexity of legal and tax rules for foreign companies operating in Free Economic Zones in India; at least one firm, according to interviews and annual reports, was losing money during the process.
And he had the sort of personality that it was difficult to remain neutral in dealing with him.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com