Leonard, an authority on swimming who has been executive director of the World Association of Swimming Coaches since 1989, believes that was a plausible, if difficult, improvement to make in 12 months.
Sequentially, the found genetic risk factors must be implemented in the development process of clinical prediction models to avoid the aforementioned problem difficult improvement of already strong models.
Felicia (2011) denotes that instructors agree with students in acknowledging the educational benefits of video games, such as an understanding of difficult concepts, improvement of spatial awareness and analytical skills, critical thinking, and problem-solving strategies.
The diagnosis of leptomeningeal carcinomatosis remains difficult despite improvement in central nervous system (CNS) imaging and cytologic examination of the cerebral spinal fluid.
The diagnosis of leptomeningeal carcinomatosis remains difficult despite improvement in central nervous system (CNS) imaging and cytologic examination of the cerebral spinal fluid (CSF)[ 1 5].
However, hircine fecundity is relatively low [ 13], and the trait is difficult to improvement by conventional breeding methods for its low heritability which ranged 0.09 to 0.14 based on the study of Zhang et al. [ 43].
While issues related to specimen preparation, imaging, and image interpretation make this approach to cell architecture difficult, recent improvements in methods, equipment, and software have facilitated the study of both important macromolecular complexes and comparatively large volumes from cellular specimens.
Microinjection does suffer from the limitation that biochemical analysis although possible is difficult, but improvements in gene expression systems have made it possible to design biochemical experiments using primary cell lines.
Although the production of large amounts of recombinant AAV is difficult, recent improvements in technology have lowered this barrier, leading to its greater use [ 24].
Of course, because both unaffected p16 mutation carriers and noncarriers alike reported improvements, it is difficult to attribute improvements among unaffected carriers to the receipt of a positive p16 test result.
This is crucial in terms of the policy imperative to improve patient safety, because without such knowledge it is difficult to design improvement initiatives which chime with professionals' experience of trying to keep their services safe and the barriers they face to doing so.
