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That has been enough to keep parts of Canada that would otherwise be covered in glaciers, ice-free.Of course, this is a difficult hypothesis to test.
(Attributing specific advancements in artifact manufacture to the threefold increase in brain size between Pliocene hominins and Homo sapiens is a much more difficult hypothesis to support, as will be discussed later in this section).
Although they offer some experimental support for this position [13], it seems a difficult hypothesis to explain in functional terms.
It is a difficult hypothesis to test, but the authors of this work make a big step toward providing an answer.
This is a difficult hypothesis to test; even the C(1)/Ø; C(2)/Ø genotype tested by Dernburg et al. (1996), would be predicted to have threads, as the C(2) was constructed using Y chromosome heterochromatin (Martins et al. 2013), and X-Y threads can be seen in XXY females.
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However, it is difficult to assume that hypothesis to be true, as they were not selected to medical school based on tasting ability (or lack of it).
Even then, with only two comparisons it would be difficult to support this hypothesis to the exclusion of possible confounding factors.
Such hypotheses are difficult to address due to the absence of multiple SCGB1A1 copies in other mammals except other equidae, such as donkeys and Przewalski horses (unpublished data).
Without this differential structure, hypotheses are difficult to falsify, and difficult to make mutually exclusive.
The incomplete knowledge of the metabolism of ANA makes this hypothesis difficult to prove.
A broad environmental sampling from worldwide geographical locations coupled with experimental biochemical validation and comparative genomic analysis allowed us to test metabolic and evolutionary hypotheses difficult to approach by using sequence data from only a few environments.
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