Childress and Jackson acknowledged that it would be difficult to guide the football with the injury.
PBL can be frustrating for tutors who find it difficult to guide discussion.
However, classical metabolic engineering rarely considers gene regulation, and it is thus difficult to guide the selection of target genes for modification.
Despite greater methodological rigour in determining studies to include in the present systematic review, it remains difficult to guide clinicians in this vital area and most of the work discussed contained small sample sizes.
Cachectic subjects are difficult to guide through chemotherapy experiencing more severe side effects resulting in progressive cachexia.
Whilst highly accurate, the complexity and size of such a setup makes the probe unwieldy and difficult to guide during insertion in a clinical environment.
But it can be very difficult to guide them to a place where they can accept that they do actually have a problem with depression when they are experiencing migraine or irritable bladder symptoms or something like that".
o Done right, growing up is filled with beautiful, difficult choices, guided by loving adults who are there to gently instruct, dole out consequences, knowing in the end, our children ultimately will be set free.
For women with a high risk of breast cancer, an experimental procedure that retrieves cells from the milk ducts may help guide difficult decisions about preventive treatment.
