However, the optimisation of these schemes (as NLP problems) would still require extensive and difficult formulations to embed the process variations.
An evaluation of the interviews showed that: a) institutions were hardly prepared for the interviews and often failed to inform their clients, reception and personnel in time; b) there had been insufficient time to train new interviewers; and c) the length of the questionnaire and difficult formulations of items were sometimes problematic.
These gaps in information impede risk assessment and make difficult the formulation of evidence-based health guidance.
The theme, dynamic stiffening, requires rather difficult mathematical formulations which may well lead to impractical engineering solutions, but several studies have been performed showing that by introducing simple variations of the thickness one is able to reduce the weight of beams while keeping constant or even increasing its fundamental frequency.
Silymarin is poorly soluble both in water and oil, making it difficult to formulate as emulsion formulation, but it was successfully formulated as proliposomes with an improved bioavailability of 3.5-fold as against pure drug in beagle dogs.
This heterogeneity makes spectroscopic study of the in ternal structure of formulation difficult.
The multifaceted of children and their parents' connotation of malocclusion makes orthodontic planning difficult; therefore, the formulation of a comprehension model should analyze socioeconomic, cultural, and psychosocial factors [2, 3] that might affect the self-perception and aesthetic appearance, as well as the desire for orthodontic treatment need.
"The general tone of pharmacists is that, I'm not going to be supporting the new generic option, now that a difficult to divert formulation is available.
These molecules are associated with poor physicochemical and biopharmaceutical properties, which makes the formulation difficult.
In low- and middle-income countries, the available liquid paediatric formulations present a number of practical difficulties: bulk transport and storage is difficult because liquid formulations tend to have short shelf lives or require refrigeration.
The participants believed that it may be difficult to find formulations for all steps of the nursing process.
