But reforming, say, the filibuster so that it isn't an everyday event would be difficult, for reasons I explain in the piece.
To say this is to indicate that you regard unlimited Medicare benefits as a sacred right, and, once you've taken that step, it becomes difficult — for reasons that Reagan gave in his recording — to oppose government-guaranteed health benefits for people who aren't senior citizens.
You know, I never bring it up unless someone else does and since you have … I tell people Ghostbusters was the most fun I had, but it was also the most difficult for reasons that I, to this day, do not understand.
Yet, this problem is difficult for reasons closely tied to the difficulties in drug discovery itself, especially the diversity in biological target ligand interaction mechanisms.
Immunohistochemistry of brain tissue sections from Mecp2-/y mice may be employed to test the hypothesis of a more pronounced growth impairment in astrocytes vs. neurons, although correct quantitation of astrocytes may be rather difficult for reasons outlined elsewhere [38].
However, discovering multiple protein biomarkers by measuring many proteins simultaneously (proteomics) in complex samples like blood has proven difficult for reasons of coverage, precision, throughput, preanalytical variability, and cost [20].
