These standards make it very difficult for developments that are being sold before construction is finished.
The ability of regimes criticised for human rights abuses to achieve notable social and economic gains poses difficult questions for development experts.
In comparison to other tropical cyclone basins, the Mediterranean Sea is generally presents a difficult environment for development; although the potential energy necessary for development is not abnormally large, its atmosphere is characterized by its lack of moisture, impeding potential formation.
Despite the genetic resemblance between humans and mice, miRNA targets may be different between the two, providing a difficult basis for development of therapeutics for human deafness.
The fact that P-gp data is smaller and very noisy makes it more difficult for AD development.
"As the French context is very difficult for the development of this activity, positive attitude and self confidence is a priority.
However, they are often designed without clear reference to theory, which makes it difficult for their development to be systematic and internally coherent.
It's becoming increasingly difficult for the development assistance world to take credit for changes that might have occurred without their interventions and to ignore the possibility that the money might have spared more people from disease if spent elsewhere.
Conventional methods of fine mapping and map-based cloning of QTLs were very difficult for the development of high-density genetic map and a series of near-isogenic lines, especially the genetic population derived from japonica × japonica or indica × indica crosses.
Limited or even no prior knowledge available for a complex disease, such as the order and the effect magnitude of a SNP-SNP interaction, makes it difficult for the development of heuristic methods.
