In the current study, no healthy controls were included, which makes inferences of causes for increased theta band connectivity difficult.
However, given the high density of neurons and synapses in the vertebrate CNS, visualizing synapses in all cells at the same time makes it very difficult to discern connectivity patterns.
However, landscape-scale goals such as increased habitat connectivity are difficult to deliver with site-based prioritization metrics.
Yet tools to map, model, predict, and change connectivity are difficult to develop, largely because of the complex, dynamic, and multivariate nature of interactions between brain regions.
Distance, the factor most affecting connectivity, is difficult to manage, although at least size and configuration of usable patches can be modified.
It was found that there is a threshold in both porosity and ionomer weight fractions, below which species percolation through the random structure becomes difficult due to reduced connectivity and increased isolation.
The longer-term adverse effects of less bandwidth, less robust and sophisticated networks, and less ubiquitous connectivity are difficult to quantify, but they are large.
Assessing whether the estimated migration rates are high enough to maintain demographic connectivity is difficult (cf. [ 10]), but our results suggest at least partial demographic independence of subpopulations, which could significantly increase the risk of stochastic extinction by lowering the demographic effective population size (Nd) well below the census size [ 93].
The uncertainty of sandbody distributions, however, can make interwell connectivity prediction extremely difficult.
The routing overhead becomes huge and inefficient, and connectivity keeping becomes difficult.
