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This can have unintended consequences such as non-clinical staff having difficult applying hand hygiene principles or discounting important hand hygiene messages as irrelevant to them.
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The most difficult applied problems are those for which different scales are important simultaneously.
He said developing the features of EdificeRex was "orders of magnitude" more difficult than applying it to the Web.
This, his personal epiphany, is difficult to apply in any prescriptive fashion.
Like all fine distinctions, this one sometimes becomes difficult to apply.
This legal test is, of course, easy to state, but difficult to apply.
Ever changing standards are difficult to apply to developing country circumstances.
This distinction is often difficult to apply but can hardly be avoided.
Regular eye drops can soothe itchy eyes but are difficult to apply even with teenagers.
But, I admit, standard metrics are difficult to apply to Murakami.
In fairness, those rules are difficult to apply on a large scale.
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CEO of Professional Science Editing for Scientists @ prosciediting.com