Sentence examples for difficult application of from inspiring English sources

A slightly more difficult application of the Mayer Vietoris sequence is the calculation of the homology groups of the Klein bottle X.

Pathways other than linear slopes have been described, but require a rather difficult application of statistical modeling [ 12].

In such situations where estimating ρ B is difficult, application of two generalised URMAs may be the most appropriate option available (Table 3), although specifically for diagnostic studies other methods may also be valuable [ 21].

The definition of the brain inflammatory profile of AD shows conflicting ideas in the literature, probably arising from the heterogeneity of the post-mortem samples and the difficult application of the detection methods [ 21].

All these models have some drawbacks, such as the complex computational process, relationships of parameters, and difficult application, so the simplifications of the flow models have to be considered.

In this respect, it is worth noting that in most of third world countries, blood transfusion is of difficult application, due to the fact that availability of blood is low and blood is often contaminated.

Nevertheless, the results are obtained by introducing multi-axial criterions, based on local stresses evaluation, reachable only with 3D refined models; this makes the approach of difficult application in multi-riveted structures.

KCl) the oxygen evolution reaction becomes more significant, and the formation of bubbles prevented or made more difficult the application of in situ techniques for the simultaneous study of the thickness and optical properties of the anodic layer.

Because monitoring neonatal urine output is difficult, the application of endogenous creatinine clearance is also limited to monitoring renal function in newborns.

Moreover in single-species networks usually the number of available functional connections (edges) between proteins can be reduced (for instance, since no sufficient data are available) and in many cases we may have highly disconnected networks, making very difficult the application of algorithms based on the propagation of the information between nodes.

The final joint has a complex external configuration with an irregular structure in places, which makes it difficult for the application of the insulation.