Sentence examples for difficult and large from inspiring English sources

It makes a difficult and large literature of the new regulatory economics accessible to the average graduate student, while offering insights into the theoretical ideas and stratagems not available elsewhere.

I think the second inaugural, which is somewhat longer it's something like 700 words or somewhere on that order but another really great speech where Lincoln is trying to do different things but also managing to encapsulate some really difficult and large ideas in a relatively short number of words.

Besides, deposition of typically 3 to 8 nm diameter QDs into mesoporous TiO2 with relative narrow pores is rather difficult, and large QDs that inserted into mesoporous TiO2 may also cause pore blocking and subsequently inhibit the penetration of electrolyte deep into the holes [8].

However, aiming at variable SpO2 target values within the first 10 min of life is difficult, and large deviations from SpO2 targets during resuscitation of preterm infants have been observed in clinical studies [52], suggesting that manual FiO2 control in the delivery room is inadequate.

He and I were working together on an extremely difficult and large mass tort claim and it looked like we had hit a roadblock.

Completing those five shifts to implement Agile across the entire organization usually amounts to changing the corporate culture, which is a difficult and large-scale undertaking.

It is understood the asylum seekers had set out for Christmas Island three days ago, but were hampered by difficult weather and large waves.

A great deal of the rugged region, which also includes small areas of China and Burma, is difficult to access and has made biological surveys extremely difficult and left large areas biologically unexplored.

In other instances, particularly with higher salinity water, meeting the leaching requirement is difficult and requires large amounts of water, possibly adding to a drainage problem.

However, if these are not centrally coordinated, performance management becomes difficult and a large number of different job descriptions proliferate [ 6].

Exome sequencing remains a difficult endeavor, and large-scale exome-sequencing studies for the identification of Mendelian disease causing genes have reported success rates around 20 35% (de Ligt et al., 2012; Yang et al., 2013).