Sentence examples for difficult, the present time from inspiring English sources

Without baseline data it is difficult the present time to evaluate the importance of these changes in our experiment.

Such dependency on hardware, acquisition, and operator make quantification and standardization of MR data extremely difficult at the present time.

Precision medicine is destined to shape the future of medical research, and in a measure dependent on EHR' contributions that is still difficult to estimate at the present time.

That said, there are many obstacles that make this difficult to achieve at the present time.

These results imply that not all mutations necessarily lead to EIAKI and that the possible genotype-phenotype correlation is complex and difficult to determine at the present time.

Unfortunately, the epigenetic changes of the entire Axin gene are currently unclear, and thus, the methylation statuses in the regions beyond the promoter and the first and second introns of the Axin gene, as well as their functional significance, are difficult to determine at the present time.

A better treatment of the feedbacks from internal metabolites than is achieved by our approach and the other approaches mentioned above requires metabolite concentrations which are difficult to compute at the present time due to the paucity of kinetic information for large scale networks.

Recent international trends suggest that there is an increase in the incidence of CD. 2 Whether this finding represents a true rise in the incidence of the disease or merely reflects an improvement in diagnostic and reporting methods is difficult to determine at the present time.

Although this difference between the overexpression and knockdown studies on ALK3 and ALK6 are difficult to explain at the present time, we propose that ALK3 and ALK6 are necessary but not sufficient for the induction of cellular proliferation by BMP-6.

Our current data with the human T-cell leukaemia cell line Jurkat suggest that the expression of CD26 may be potentially linked to high topoisomerase II α level in selected T-cell malignancies, which are generally aggressive and often difficult to treat at the present time.

One note of caution however, is that property outside of the major destinations might be difficult to reach at the present time.