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I would point out that happened some time ago, so it's very difficult currently to ever get a real-time handle on replacement rate.
Some of those are even ethnically associated with agriculturalist vs. nomad – conflicts (e.g., in Rwanda, Burundi, Congo's Kivu region, Dafur, southern Mali, parts of Ethiopia), whereas this seems difficult currently to reconcile for regions such as northern Ireland, "Kurdistan", northern Israel and Lebanon, northern Ivory Coast and parts of central Asia.
42 Important methodological limitations and inconsistencies among the studies identified make it extremely difficult, currently, to justify policy action taken on the basis of evidence alone.
Physiological studies of the ligands, PACAP and VIP, in teleosts are not very numerous and certainly do not encompass all the actions assigned in mammals making it difficult currently to assign possible biological roles to the duplicate receptors.
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However, at this time fusion is just too difficult and currently consumes more energy than it produces.
Control of bleeding from major arteries in the upper-GI tract remains difficult with currently available endoscopic devices.
Obtaining an optimal solution to the MIP model is difficult, and currently only problems with a limited number of departments can be solved to optimality.
Mostly we discussed health policy, but we covered general politics, too, and Healey was also startlingly candid about how difficult it currently is for Labour to get anyone to take notice of what it's saying.
Brown 'will still be PM by Christmas' He said he was "absolutely confident" that Brown would still be prime minister by Christmas because he was focused on dealing with the difficult issues currently facing the country.
"We have wanted to remove this invasive pest for a long time but this has proven very difficult using currently available tools on an island the size of Grand Cayman, so we have been looking for new approaches," Petrie said.
Determining bone union and the timing of frame removal can be difficult, and currently no gold standard method exists [1].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com