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Warny, M. et al. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe.
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Binary toxin (CDT) is frequently observed in Clostridium difficile strains associated with increased severity of C. difficile infection (CDI).
In conclusion, infection with C. difficile is associated with 22.4% and 14.2% treatment failure and 27.1%andd 24.0% recurrence after treatment with metronidazole and vancomycin, respectively.
Additional studies are needed to evaluate the risk for C. difficile infection associated with different fluoroquinolones.
Infection with C. difficile is associated with recent use of antimicrobial medications and with residence in hospitals.
Recent reports document the emergence of an epidemic strain of C. difficile, NAP1/BI/027, associated with increased virulence (2, 3 ).
The objective of our study was to determine the characteristics of C. difficile isolates associated with an outbreak of infection in a tuberculosis unit.
In one experience, an outbreak that was caused by a clonal isolate of clindamycin-resistant C. difficile was associated with increased use of clindamycin despite the presence of infection control practices [ 32].
The CHW visits the mother 2 3 days after starting the antibiotic to screen for symptoms of C. difficile diarrhea/colitis (associated with clindamycin) and hemolytic anemia (associated with Macrobid).
Model results suggest that 20% (13.3%–26.8%) of deaths in persons >65 years of age caused by infectious intestinal disease other than Clostridium difficile were associated with norovirus infection in this period and that 13% (7.5%–18.5%) of deaths caused by noninfectious intestinal disease were associated with norovirus.
Clostridium difficile associated colitis.
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