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The phrase "differs profoundly from" is grammatically correct and commonly used in written English.
It is typically used to describe a significant or extreme difference between two things or ideas. Example: The new product design differs profoundly from the old one in terms of functionality and appearance.
Exact(18)
Wade then states that evolved differences in these races are the key explanation for social differences in histories, economies and societies between them -- why "Chinese society differs profoundly from European society, and both are entirely unlike a tribal African society" (p. 123).
Thought-crime may be next.All this suggests Sheikh Hasina's dream for Bangladesh differs profoundly from that cherished by her countrymen.
Hazem Ghurab, the veteran journalist who is running the channel, says Egypt 25 differs profoundly from his business-funded competitors.
"If you spend any time in Africa, you learn very quickly that the situation on the ground differs profoundly from the popular perception and from media coverage..
"If you spend any time in Africa, you learn very quickly that the situation on the ground differs profoundly from the popular perception and from media coverage.
One subtype, here designated as slow climbing, differs profoundly from the other subtypes of the category, being somewhat ponderous and devoid of elements of leaping or jumping.
Similar(42)
"These men were my rivals and my neighbours, people whom I admired and differed profoundly from".
De Gaulle concluded that "the nature, the structure, the very situation that are England's differ profoundly from those of the continentals".
In the 16th century it embraced a stark, Calvinist Protestantism that hailed from Geneva, and differed profoundly from the middle way of the Church of England.
In "Far From the Tree, Andrew Solomonn's book on families with children who differ profoundly from their parents, he developed the idea of horizontal and vertical identity.
"In short, the nature and structure and economic context of England differ profoundly from those of the other states of Europe".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com