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Seasonal variation in birth of patients diagnosed with a specific disease, which differs from the underlying seasonality of births in the general population, suggests an environmental factor operating at conception, during pregnancy or in the neonatal period.
Seasonal variation in births of patients diagnosed with a specific disease, which differs from the underlying seasonality of births in the general population, suggests an environmental factor operating at conception, during pregnancy, in the neonatal period, or later in childhood.
The millimeter-thick skin of the ocean, called the sea surface microlayer, differs from the underlying water.
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These assorted surface sediments often differed from the underlying bedrock in their lithological composition and texture, and were delimited by lithological discontinuities.
It is known that postal surveys are susceptible to positive selection bias [ 28, 29], and respondents tend to differ from the underlying population [ 30].
It is important to emphasise that this mechanism differs from that underlying the higher agonist sensitivity in regions with re-sealed t-tubules as this phenomenon was unaffected by sustained depolarisation of the t-tubules (Fig. 4).
In the elbow, the distal condyles of an alligator humerus are composed of large cartilaginous condyles that differ substantially from the underlying bone's shape (Fig. 5A, B).
There is concern over the effectiveness of P4P schemes where sustained quality improvement may differ little from the underlying trend [ 19, 20].
Our data show that mutant VAPB and mutant seipin accumulate in different inclusions when coexpressed, indicating that the mechanisms that operate in the formation of VAPB inclusions differ from those underlying the formation of ERPO.
These mechanisms differ from those underlying the canonical cellular differentiation model in which a sequential deposition of DNA methylation and histone modification marks progressively restricts the chromatin landscape.
KChIP1 is targeted, through N-terminal myristoylation, to intracellular vesicles that appear to be trafficking intermediates from the ER (endoplasmic reticulum) to the Golgi but differ from those underlying conventional ER Golgi traffic.
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