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The suggestion was put forward that there might be a difference between the results from studies executed in high-risk and low-risk areas for oesophageal carcinoma because of the differing time of diagnosis of the cancer.
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Consider how crime hot spots may change to different locations, to different times, or hot spots for different crime types may occur simultaneously, or at differing times of the day or days of the week at the same location.
At differing times of day and in various seasons haystacks absorb the light from diverse parts of the color spectrum.
Before the facility reopened, the Guam Waterworks Authority distributed water to the island at differing times of the day to ration the limited supply.
To explore this question, simulations were run with differing times of initiation and duration of stromal-directed therapy.
Earlier publications have studied trauma, surgical and medical ICU patients separately with differing times of assessment [ 2, 3, 9, 10].
Finally, as V-ATPase plays an important role in synaptic activity, it is possible that neuronal activity is modulated in a time-of-day manner in the two species, yet in opposite phases, again concordant with the differing times of behavioral activity in each mosquito.
The variety of risk estimates in the various studies may reflect differing time frames of exposure measurement, different compositions of PM, different characteristics of the exposed populations, and considerable statistical uncertainties.
This may in turn be due to the limitations of the 6-hydroxydopamine (6-OHDA) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) models of PD in reflecting the pathophysiological mechanisms, the differing time course of disease development, and the effects of medication in humans.
Moreover, our experiments indicate that the original mineralogy of presalt CaCO3 could have been calcite or aragonite, but the differing time scales of precipitation between CaCO3 and Mg-silicates would have tended to skew the Mg/Ca ratio in solution towards elevated values which favor aragonite.
Barriers included those intrinsic to research methods, such as differing time lines of methods leading to separate analysis and publication; those related to the skills and preferences of researchers, such as different team members undertaking different components of a study; and structural barriers, such as different journals emphasising either qualitative or quantitative research.
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