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TGF-β1 has been targeted to the mammary gland using two different promoters, and the resulting mice showed different phenotypes [ 7, 8*], probably due to the differing temporal and spatial patterns of expression of the two promoters.
Importantly, the differing temporal and spatial resolutions of individual methods are not merely technical constraints that invariably compel cautionary interpretation of changes in the extracellular concentrations of neurotransmitters, but these resolutions impose on the very conceptualization of the functions of neurochemically defined groups of neurons.
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Spatial clustering of cholera cases was detected at different temporal and spatial scales.
There is ample precedent for maintenance in a given genome of co-existing structural genes whose gene products catalyze the same reaction, but which function in differing temporal or spatial modes in different pathways.
Although both are intermediate filaments, they differ in temporal and spatial expression patterns in astrocytes.
This suggests that in humans, tissue aging differs by temporal and spatial means.
These modalities, which differ significantly in temporal and spatial resolution, have inherently different technical requirements.
Thus, ghrelin activates Akt pools that differ in their temporal and spatial distributions, suggesting to have different physiological targets.
The temporal and spatial response differed among soybean genotypes with different numbers of SDS resistance genes.
We used day-of-year scaling factors to estimate AADT for bicycles and pedestrians and found that temporal and spatial patterns differed between modes.
Temporal and spatial differences in expression are likely.
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