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The discrepancy between this study and our experimental data, apart from species differences, may result from differing preconditions between the two study designs.
Their perception was influenced by differing preconditions related to the competitive situation locally as well as variations in management skills.
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This is necessary, because the various approaches were initially developed for different scenarios and thus differ in their preconditions.
Moreover, while the Nivel study explored preconditions for implementation such as 'good collaboration between partners' or 'an independent role of the case manager', they did not investigate if these preconditions differed between case management models, nor did they study different phases of implementation.
The type of non-RCT considered also differed: IQWiG's precondition for inclusion was the existence of a concurrent control group; studies with a historical control group were excluded, as systematic bias may arise from time trends in the outcomes of study participants [ 38].
Despite the differing effects of individual sulfonylureas on the SUR receptors and myocardial ischemic preconditioning, there are also differing effects regarding the risk of hypoglycemia, independent of their SUR-binding characteristics, which may be influencing mortality (13).
Due to varying preconditions, individual PCCs may have differing rates although guidelines for a rational antibiotic use are followed.
The preconditions have differed considerably between the countries resulting in a wide range of estimates of the repeatability and the reproducibility (precision) of fat and muscle thickness.
Furthermore, we found comparably high retention rates in all treatment cohorts, even though the patients in these cohorts differed perceptibly in clinical preconditions.
However, as both groups differed significantly in age, the preconditions for calculating and interpreting an Analysis of Covariance were not fulfilled [ 33, 34].
Although mechanisms of hypoxic preconditioning and IPC may differ, few genes were found to be differentially regulated in both types of preconditioning protocol.
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