Furthermore, patients classified as low risk based on the 'cell death' signature, but not those classified as high risk on this basis, could be separated into groups of differing outcome on the basis of the 'cell cycle' signature (p = 0.015 and 0.67, respectively; Fig. 7D).
These findings suggest that different models of home and community care have differing outcomes depending on their focus - case management focuses on consumer care, integrated care on an efficient system and consumer directed care on giving control to the consumer.
Studies involving matings of mice that over-express WT hSOD1 to mice that over-express mutant hSOD1 have reported differing outcomes depending on the strain of WT hSOD1 mice used.
Depending on the dimers formed, distinct sets of genes are transcribed which results in differed outcomes.
Even if different surgical procedures are likely to differ in outcome on hand pain and function [ 4], it is not obvious that there is a need for specifically developed instruments for each surgical procedure.
These confounding variables may play differing impacts on outcomes but, in general, have not been consistently addressed.
Compared with the intrinsic subtypes, methylation-based clustering provided somewhat better distinction of patients differing in outcome based on log-rank P values.
However, after statistical adjustment for sociodemographics, dementia severity level, time since onset of cognitive decline and probable AD diagnosis at baseline, the groups significantly differed on only one outcome: the misdiagnosed were less likely to be depressed/dysphoric.
In the same way, there was a significant interaction between the variables, meaning that the effects of the exposure on the outcomes differ depending on whether another variable (the effect modifier) is present.
The meta-analysis of studies relating to colonization and/or infection with MRSA shows the potential effect of differing study designs on resistance outcomes.
