However, the X-Y linker region is poorly conserved amongst PLCζ isoforms, except for the presence of positively charged amino acids, prompting speculation that differing motifs in this region may underlie species-specific patterns of Ca2+ oscillations amongst mammals [ 33, 36, 89].
The differences observed between the two curves likely reflect the lack of experimental data for mononucleotides at certain repeat numbers (5 7, 9), as well as fluctuations due to the limited number of TRs differing in motif composition examined experimentally at repeat numbers 8 and 10.
This is compared to an element/motif approach and applied to a data set of Lapita archaeological ceramics from Fiji and Tonga, regions that are known to share motifs, but differ in motif application and layout.
The motif region significantly differed among motif lengths (H = 28.4, P < 0.0001), but there was no consistent trend or relationship across the motif lengths (see Table 2, Fig. 4).
However, many non-homologous proteins share molecular function as a result of convergent evolution, [91] and variations can produce enzymes with similar function but differing sequence motifs [92].
Thirty-eight entries were identified where matching primer sequences (forward and reverse) were found but with differing repeat motifs reported (19 primers total).
In this research, we designed and genetically engineered three novel rBCVs with similar sequences that differed in motifs arrangement and motif abundance: MPG-2H1, 2TMPG-2H1 and 2RMPG-2H1.
In cases where the motif differed in composition (38 entries total, 19 primer pairs), seven motifs differed in repeat frequency, eight contained entirely different motif configurations, one was a complementary motif of equal length, and the last case consisted of three complementary motifs with differing repeat frequencies.
If we assume that putatively shared motifs are in fact used by both promoters, we find that although for the majority of the genes the first two promoters differ in motif composition, more promoter pairs are similar than we would expect at random (Table 4, "shared motifs allowed" and Figure S3 [see Additional file 6]).
For a given allele length, mutation rate differed among motif types.
