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It has long been known that not all TF DNA binding events are created equal; for example, different mutants in Hap1 that do not affect DNA binding can selectively affect the expression of different genes, presumably due to differing interactions with cofactors (Turcotte and Guarente 1992).
To this end, we consider (i) the differing interactions of the receptors with CTR1, (ii) the specific interaction of the receptor ETR1 with the regulatory protein RTE1, and (iii) evidence that as yet undiscovered proteins may account for some of the non-overlapping functions among the ethylene receptor family.
In that respect a film, like a tape, like a play, is not a fixed entity, but may have differing interactions as the world around it changes, may develop other meanings the older it gets.
To the extent that DHT competes with T for AR binding sites, it does not interfere with sex behavior-promoting actions of T. Rather, MSB is facilitated by co-administration of the two hormones, which may attest to their differing interactions with the AR, to unexplored effects of DHT metabolites, or to the greater duration or amount of androgen exposure in hamsters treated with both hormones.
Therefore, the clinical outcomes, survival and immune response following HBV vaccination may be the diverse results of the differing interactions of various cytokines at specific cellular, organ, and system targets.
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While Skr1 (which is thought to have a function similar to that of the human SKP1) interacted with most of the F-box tested, and the remaining Skr displayed differing interaction capabilities.
Differing electrostatic interactions lock 192– and [ 19·H]− in two different conformations.
The potential alterations exhibited by ligand-bound bSCAD are smaller than those of pMCAD, while their directionality and magnitude suggest differing enzyme analog interactions.
Mass spectrometry reveals differing protein interactions between DDB1 and distinct DCAFs, the substrate recognizing components of the E3 complex, between cell types.
We note that as in [5] but in contrast to later work [11, 20] self-interactions can differ from interactions with other neurons, that is, (mathbf {G}_{jj} neq mathbf {G}_{ij}).
This interaction differs from other interactions with the duplex region, which also contributes to additional binding affinity but cannot properly position the P/T junction at the pol active site for catalysis.
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