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In humans, TXA2 signals through two TP isoforms termed TPα and TPβ that are identical for their N-terminal 328 amino acids differing exclusively in their carboxyl terminal (C -tail domains [14–16].
Interestingly, our search for paralogous target genes in the complete genomes of the host organisms also unearthed additional ORFs that include perfect variable repeats differing exclusively in A-positions from their corresponding TR.
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In this context, revenue sharing increases competitive balance if, with all other factors being equal, the clubs differ exclusively in terms of the impact of absolute quality on revenue.
The present research opted for a variant of the new scoring algorithm that differed exclusively in terms of its outlier treatment.
It must be emphasized that the initial WT and mutant viruses differed exclusively in substitution M296I since they were reconstructed from infectious plasmids, as described in Materials and Methods.
Most closely related species of insects differ exclusively or predominantly with regard to sexually dimorphic traits [ 1, 2].
Therefore, we investigated CNVs in completely homozygous chromosome substitution lines, which differ exclusively in the origin of the second chromosome but are otherwise genetically identical.
This complementation strategy therefore successfully generated hESCs that differed exclusively at the TERT locus by expressing TERT either from its wild-type promoter or from a promoter that contained one of the cancer-associated point mutations.
Using genome editing of the endogenous TERT locus we generated a panel of three hESC lines that differed exclusively at a single position in the TERT promoter associated with cancer.
The generation of genetically matched controls that differ exclusively in well-validated susceptibility variants for maladies is a generally applicable solution to the key problem of distinguishing pathologically relevant phenotypic changes from other background-related variations (Soldner et al, 2011; Reinhardt et al, 2013).
We also evaluated whether the probability of detecting each arsenic species differed between exclusively breastfed and exclusively formula-fed infants using Fisher's exact test.
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