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These data suggest that the differing degrees of sensitivity to PI3KIs may be because of defects residing downstream of AKT and/or because of parallel independent survival pathways that antagonise the cytocidal effects of the PI3KI.
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The diversity panel consisted of 187 sorghum genotypes from six West and Central African countries, consisting of eight racial groups (3 major- and 5 intermediate-racial groups) and included breeding lines and landraces, with differing degrees of photoperiod sensitivity and internode lengths.
Officials face a difficult task in coordinating action among countries with different currencies and differing degrees of economic distress.
Each of these different materials provides differing degrees of friction, power, and control.[1].
We hypothesize that the observed differences between cancer types may be attributable to differing degrees of cellular heterogeneity, or to differing degrees of TERT sensitivity.
Closer examination revealed minutely differing degrees of density in the black of the shadows.
Across Europe, there are even differing degrees of interest in sorting out the larger questions.
The optional fare in the baskets is surprisingly varied, reflecting regional customs and differing degrees of assimilation.
Ryder Cup rookies come in all shapes and sizes, temperamentally unalike and with differing degrees of experience.
There are an estimated twenty-five thousand armed insurgents in Afghanistan, with differing degrees of loyalty to the Taliban.
All brushes have identical grafting density, but differing degrees of polymerization.
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