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Instead, the aim was to generate an early estimate of value from an Statutory Health Insurance (SHI) perspective to identify attractive target patient groups, inform tentative value-based prices for differing assumptions of effectiveness, and derive implications for including such value considerations into product design.
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Sensitivity analysis was carried out with a range of differing assumptions, providing a range of cost-effectiveness ratios as high as £21 000 or as low as around £6000.
The results suggest that depending on the combinations of differing assumptions on the possible long-term vaccine effects, the cost-effectiveness profile of each PCV may vary widely.
Differences likely reflect differing assumptions and methodological biases of the various methods.
On the basis both of differing assumptions about evaluation conventions and of reasoned speculations as to how test parameters and costs might behave under screening, the model generates cost effectiveness ratios as high as around £20,000 and as low as around £7,000.
These solutions of the 2-pool model are based on differing assumptions and involve differing degrees of complexity, so their individual advantages and limitations are not always obvious.
Surveys in the state also diverge on the current state of Moore's political fortunes, in no small part due to differing assumptions about voter turnout.
Prognostic gene signatures like the wound and hypoxia signature differ by assumptions of cellular growth.
These models mainly differ in the assumptions of marker effects contributing to total variance.
The EFHIAs each had differing degrees of perceived effectiveness.
The model was most sensitive to assumptions of the effectiveness of ART in reducing HIV transmission probabilities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com