Differently from this study [42], we found that the probability of never having smoked before the start of CH was similar between females and males, not higher among females.
With hindsight, there are some things that we would do differently in this study.
This might lead to a greater decrease in EE (kJ/d) compared to a reduction in FM only and may explain why BMR was affected differently in this study.
Moreover, responsiveness was assessed differently in this study since the analysis was performed in students rather than neck pain patients and participants were not treated between repeated measurements.
Besides CDPKs, further transcripts of proteins with a dependency of calcium ions as second messengers have been identified as differently expressed in this study.
Furthermore, other studies have measured JOLs differently than in this study.
Proteins, known from other glaucoma studies, such as zink-finger protein (CNPB), were detected to also be differently regulated in this study (Fig. 2).
For example, the study conducted in 2005 did not define 'smoker' and used a selective sample as their population while in the study in 1999, 'smoker' was defined differently than in this study.
Further, by querying the Urinary Proteins Biomarker Database we found that some of the proteins differently excreted in this study were also identified as urinary markers of diabetic nephropathy, ureteropelvic junction obstruction and IgA nephropathy therefore we speculated that they might indicate the same injury sites or pathophysiological processes.
In this study, differently from (Convertino and Hedberg 2014a), Manitz et al. (2014), and (Brockmann and Helbing 2013), deep uncertainty in reported outbreaks is introduced.
