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In the HMF, reduced differentiation was observed, which is consistent with the observed increase in the production of NPCs/NSCs.
Extended Data Fig. 2 A MG-derived rod differentiation was observed across the whole retinal section.
However, no adipogenic differentiation was observed within the preadipocyte-seeded scaffolds.
The highest suppression of NSC differentiation was observed on HC film with 3 μm pore specifically.
No Th1 or Th2 differentiation was observed, as assessed by interferon-γ or IL-4 accumulation.
No osteochondrogenic differentiation was observed in cells incubated in the control medium.
Immunofluorescence (IF) assay for α-SMA expression revealed that WT BALF induced differentiation of fibroblast into myofibroblast, but no differentiation was observed with Ninj1 KO BALF (Fig. 4G).
A highly significant genetic differentiation was observed among samples that did not follow an Isolation-by-Distance or Isolation-by-Time pattern.
Reduced differentiation was observed in the heparin microparticle group as compared to PEG and no microparticle-containing groups.
In first-passage cultures, an osteoblastic differentiation was observed in both cases as the cells expressed ALP and formed mineralized bone-like nodules.
Optimal osteogenic differentiation was observed on discs with surface topography characterized by Ra ranging from 0.77 to 1.09 μm and RSm ranging from 53.9 to 39.3 μm.
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