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Expression of proteins and genes relevant for endothelial function and differentiation was increased after induction.
Cell differentiation was increased in all EDM modified surfaces compared to controls and early differentiation was promoted on the dual-topography surface.
Importantly, FoxC2, a crucial regulator of cAMP pathway that promotes BAT differentiation, was increased in the WAT of Fsp27−/− mice.
In support of this model, we observed that osteoclast differentiation was increased in the absence of Id1, leading to increased secretion of CTSK.
Osteoblast differentiation was increased in both wt and Fas -/- mBSA-injected mice.
As expected, the mammary content of β-casein, an indicative of the degree of differentiation, was increased (P < 0.001) in I rats compared to Null rats.
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Analysis of over-represented terms among probes with temporal expression differences supported a model in which processes such as cell metabolism and cell growth were declining while differentiation was increasing.
The results indicated that the secretion of a cartilage-specific extracellular matrix and gene expression concerned with chondrogenic differentiation were increased by CMP motifs.
Another characteristic of megakaryocyte differentiation is increased surface expression of integrin αIIbβ3 [34].
Thus, in Id1-deficient mice, myeloid differentiation is increased, indicating that Id1 normally acts to maintain myeloid progenitors in an undifferentiated state.
In ovarian cancer, however, PPAR γ levels independent from tumor differentiation are increased [ 8].
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