Sentence examples for differentiation transition from inspiring English sources

We also show the expression of sf1 no earlier than D14, a period that succeeds a potentially important differentiation transition point (see below).

A key remaining question is how individual epidermal progeny cells undergo distinct differentiation transition stages, including responses to external signals or potential changes in chromatin structure.

The strong slow-down of proliferation in the first differentiation transition partially continued in the second differentiation step, whereas most of the decreased cell cycle genes did not change further in the second transition.

Specifically, the results suggested that relative differences in the decay rates of particular genes may be important for the establishment of the robust pattern of differentiation transition observed during floral organ determination.

With these maps of the differentiated state in place, a central task is now to unravel the chromatin dynamics that enables these differentiation transitions.

Recent studies have shown that CLCA1 could increase cell differentiation through the regulation of the proliferation-to-differentiation transition.

The nucleus of epidermal keratinocytes (KCs) is a complex and highly compartmentalized organelle, whose structure is markedly changed during terminal differentiation and transition of the genome from a transcriptionally active state seen in the basal and spinous epidermal cells to a fully inactive state in the keratinized cells of the cornified layer.

Notch signaling, which is activated at stage 6/7, induces follicle-cell differentiation and transition from the mitotic cycle to the endocycle in the FE.

Caco-2/AQ cells undergo spontaneous differentiation on transition into the post-confluent state, as indicated by a steep rise in differentiation markers, i.e. alkaline phosphatase activity (cf. Table 1).

Alternatively, the signal may correspond to differences in myocyte progression through proliferation and differentiation, the transition through which is known to be accompanied by various changes in matrix-mediated adhesion [ 29].

In contrast, the loss of normal tissue structure and the dysregulation of genes involved in modulating growth and differentiation indicate transition of the disease into a more advanced stage [ 3].