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Clonal differentiation studies revealed that CXCR6+ cells within the αLP population differentiate into all ILC lineages but not T- and B-cells.
Biocompatibility studies, namely metabolic activity, mineralization and differentiation studies were conducted with human osteoblastic cell line SAOS-2.
We see multiple applications for this novel system in hepatocyte maintenance and stem cell differentiation studies.
In differentiation studies, the NF scaffolds displayed more uniform matrix and mineral production throughout.
Cell differentiation studies of fibrin incorporated hydrogel scaffolds showed better differentiation was confirmed by Oil Red O staining technique.
Differentiation studies showed an increase in osteoblast differentiation on fibronectin substrates while collagen substrates lacked osteogenic differentiation.
Adipogenic differentiation studies with human adipose-derived stem cells (ASCs) suggested that stiffness influenced ASC adipogenesis on the foams.
Moreover, it was observed during the differentiation studies that MG63 cells seeded in both microfibre scaffolds possessed a significantly higher ALP activity than in nanofibre scaffolds.
Such Si/PS substrates become thus ideal candidates for the study of alternative microenvironment conditions to the standard flat two-dimensional plates used for hMSC differentiation studies.
Future differentiation studies using these lines may offer insight on specific disease pathophysiology and aid the design of protective drug therapies.
Genetic differentiation studies showed inherent differentiation and infrequent gene flow between IYSVBR and IYSVNL genotypes corroborating the geographical confinement of these genotypes.
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