"Clicks disproportionately go to the highest-placed search ads, with little room for differentiation," states the L2 report, which examines what it calls "evolved retailers" – online merchants that have opened brick and mortar storefronts.
Superficial cells showed various differentiation states.
For instance, intermediate spectra of macrophage differentiation states were reported by Finn et al. [23].
However this method requires further sorting strategies for continued monitoring of resultant cell differentiation states.
The cellular microenvironment is recognized to play a key role in stabilizing cell differentiation states and phenotypes in culture.
Because artificial scaffolds can regulate the differentiation states of ES cells, compatibility between the cells and artificial scaffolds is important.
In one example, the SMART-seq protocol was used to profile full-length mRNA from 430 primary glioblastomas to reveal an intratumor spectrum of differentiation states [63].
Blood cells provide a snap-shot of many lineages and differentiation states within the immune system including the sites of vaccination.
I found that these profiles, while explicitly uncorrelated with the respective transcriptional "identities" by construction, associate strongly with cell differentiation states.
These findings suggest that CD4+ and CD4− NKT cells may represent unique differentiation states.
Gliomas display a striking cellular heterogeneity with a hierarchy of differentiation states.
