Activation and expression levels determine whether Stat3 functions in a self-renewal or a differentiation role in mESCs.
Actually, this growth and differentiation role for GATA-3 in normal mammary epithelial cells has been already widely described [ 9, 22, 34, 38].
These reports suggest the growth inhibitory and differentiation role of PPAR β in colon and skin carcinogenesis and contradict the growth-promoting reports described previously.
The literature review was based on a search which was conducted using the following key terms: physician(s) assistant, PA, utilisation, deployment, employment, impact, costs, cost benefit, evaluation, working relationship, role differentiation, role delegation, substitution.
Consistent with pro-differentiation roles of apoptosis, we showed that a small-molecule activator of CASP3, PAC1, markedly downregulated the pluripotency program in both wild-type and Dgcr8−/− ESCs.
To describe the role differentiation and role transition of health care providers involved in a community-based, early assisted discharge, hospital-at-home scheme for COPD exacerbations.
Perhaps in combination, these results suggest that Asense may also have a pro-differentiation role.
Furthermore, Mash1 is consistently found to promote neuronal differentiation (Sommer et al, 1995; Tomita et al, 1996), which is consistent with a pro-differentiation role for Asense.
Using primary cultures of normal human prostatic epithelial cells as a model of basal cells, we showed that MAO-A prevents their differentiation into secretory epithelial cells [ 6], consistent with an anti-differentiation role of MAO-A in neural stem cells [ 7].
