For differentiation into an oriented and non-oriented cell formation, an angle of 90° was set as threshold value.
However, under some initial conditions varying the physical matrix, seeding density and the proportions of exogenous growth factors (available upon request), we have not yet successfully oriented hNCC differentiation in vitro.
During the fusion and differentiation process the myotubes spontaneously oriented along the long axis of the cantilever, facilitating bending of the cantilever.
It was pathologically diagnosed as ACA; the cyst was lined by cells with normal acinar differentiation; cuboidal cells with round, basally oriented nuclei and eosinophilic granules in its apical cytoplasm.
Further outgrowth of the limb skeleton is governed largely by the coordinated homeostatic expansion and differentiation of chondrocytes within the longitudinally oriented structure known as the growth plate, and osteoblasts in immediately adjacent perichondrial tissue [7], [8].
This process can ultimately lead even to the differentiation of radial series of normal, axially oriented tracheids next to tangentially oriented ones.
In vitro oriented collagen and a combination of differentiation factors (NGF, neuregulin-1, TGF-β) induced Schwann cell alignment to some extent.
STR (control variable) = a dummy variable describing whether the core company strategy should be described as oriented towards costs (value = 1) or differentiation (value = 0).
We created a gene expression signature to measure neuroblast maturation, adapted it to a high-throughput platform, and screened a diversity oriented synthesis-generated small-molecule library for differentiation inducers.
First, aligned CNTs showed a higher rate of proliferation and differentiation for the hMSCs than the CNTs that are randomly oriented as seen in Fig. 7 [78].
The regrowth, proliferation, and migration, of Schwann cells (S42) and the differentiation of rat pheochromocytoma cells (PC12) were greatly accelerated on the aligned oriented mats as compared to the randomly oriented mats during in vitro cell cultures.
