Furthermore, MPM allowed the differentiation of cellular features such as nuclear pleomorphism, which is an important biologic characteristic reflecting tumor grade, degree of differentiation, and proliferation.
This suggested the hypothesis that loss of normal cortical differentiation and gain of features associated with wound healing are important biological features associated with lethal ccRCC.
Two powerful pattern recognition algorithms (support vector machines and probabilistic neural networks) have been designed and developed in order to quantify the power of differentiation of the introduced features.
In S. incrustans, however, there was some differentiation of certain microscopic features, for example, wall thickness of the trama hyphae and the size of the basidia and basidiospores.
Investigating co-occurrence of multiple histone marks facilitates the differentiation of more subtle features in chromatin state, such as identifying tissue-specific strong and weak enhancer regions (Ernst et al., 2011) and changes in co-occurrence patterns between evolutionarily distant species (Ho et al., 2014).
Two types of non-spatial information are represented: (1) time series data from resting-state functional MRI measuring brain activation; (2) network properties derived from structural connectivity data for different groups of subjects, which may help guide the detection of differentiation features.
These observations support the concept that RARRES3 prevents the initiation of lung metastatic lesions by enforcing the retention of differentiation features.
A large number of higher taxa contain species restricted to subterranean habitats, and most of these species show convergent differentiation in a suite of features related to the absence of light [ 1, 2].
Visual detection of differentiation features can also potentially discover image-based phenotypic biomarkers for brain diseases.
14 This subpopulation of cells has a capacity for self-renewal and multi-lineage differentiation, known features of non-CSCs.
