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Also, the existing thresholds may not show any differentiation of either as object or shadow for those pixels whose values of saturation and hue are undefined.
Partial differentiation of either cell type was achieved by culturing cells in serum-free medium, essentially as described previously [20].
Consistent with the transcript analysis, western blotting shows there is no change in the total CXCR4 expression upon differentiation of either wild-type (WT) or 5T4 knock out (5T4KO -ES cells (Figure 1C).
While these data establish some molecular and in certain cases, lineage and clonal relationship of neurons and hair cells, the molecular basis for the distinct differentiation of either cell type has not been investigated beyond the transcriptional regulation of Neurog1 and Atoh1 [20] or short range interactions mediated by delta-notch [23].
The function of ARID1A in differentiation of either tissue type has not been investigated.
Consistent with these data, differentiation of either ESCs or NSCs caused a dramatic decrease in nuclear Hdac6, accompanied by increased Hdac6 within the cytoplasm.
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The differentiation time of either differentiating spermatogonia or pachytenes has negative effects on their respective downstream cells.
Thus, coupling the good proliferation and differentiation capacities of either adult mesenchymal stem cells (MSC) or embryonic stem cells (ESC) with the textural and chemical properties of the PSi substrates provides an interesting approach for therapeutic use.
These models included: 1) TGFβ-induced EMT, which provided a look at the active transition between states; 2) a panel of 22 pancreatic cancer cell lines, which represented terminal differentiation states of either epithelial-like or mesenchymal-like; and 3) actively-migrating and stationary cells, which provided a look at the mechanism of migration.
However, the role of these products in the proliferation and differentiation process of either human or murine lymphocytes have not been explored.
Investigating new ways of differentiation to either increase the yield or quality of cells may pave the way for innovative cell replacement strategies using iPSC-derived mature hematopoietic cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com