Only a small number of the myonuclei of proliferating mononucleated cells were found to express myogenin, whereas the majority of the nuclei were myogenin positive in the multinucleated differentiated cells confirming their more advanced differentiation level.
Assessing the differentiation level of tumor is often conducted in the clinic, and the poorly-differentiated tumors are closely associated with patient prognosis.
The differentiation level of the bone cells may influence their radiation sensitivity.
Cell clone specific variations (subclones 4 and 24) in the radiation sensitivity may be due to the differentiation level.
We demonstrated that culturing HepaRG cells at high density maintained high hepatocyte purity and differentiation level.
The cells on composite scaffolds showed a higher alkaline phosphatase activity which suggested a higher differentiation level.
The osteogenic differentiation level of cells cultured on the films was strongly dependent on surface potential and reached the optimum at 391 mV in this system.
After being cultured in conditioned medium for 30 days, the cells' alkaline phosphatase (ALP) activities on the scaffolds were studied in situ to compare their differentiation level.
In conclusion, the cell line with the highest differentiation level (MLO-Y4) displays lower radiation sensitivity, regarding the shoulder width of the dose effect curve, compared to the less differentiated osteoblast cell lines.
We also allow the local firm to imitate MNE's product differentiation level as well as its Process R&D; and we find that, under spatial Hotelling price competition, the local firm has no incentive to imitate the MNE's product design, i.e. the level of product differentiation of the MNE, at Nash Equilibrium.
