Sentence examples for differentiation itself from inspiring English sources
TRPC1 may be associated with differentiation itself; TRPC1 was required for neurite outgrowth in differentiating PC12 cells but was independent of SOCE [51].
Prior to this theory, nuclear transfer was believed to work only if the nucleus used as the donor for nuclear transfer came from a cell that was totipotent i.e., having the ability to differentiate into any type of cell in the body and therefore possessing no characteristics of differentiation itself.
Additional requirements for elucidating AD mechanisms might require better control of differentiation itself.
β-tubulin III therefore appears to be a marker of neuronal lineage and not of differentiation itself.
To determine whether neuroendocrine differentiation itself has prognostic significance, we pooled the NEC and IMC-NOS cases together and performed multivariate analyses based on all the known prognostic factors in addition to neuroendocrine differentiation.
Furthermore, when all NEC and IMC-NOS cases were pooled together, neuroendocrine differentiation itself was an adverse prognostic factor independent of other known prognostic factors, including age, tumor size, nodal status, histologic grade, estrogen/progesterone receptor status, and therapy.
The results demonstrate that, while proliferation may be required for B cells to reach a state at which they are capable of differentiating into plasma cells, ongoing B cell proliferation is not required during the differentiation process itself.
But paradoxically this primal absence of any distinguishing origin, this ubiquitous in-difference of all differentiation, is itself the ultimate origin of all thing-events in their mutual differentiations and co-relativity.
Interestingly, the up-regulation of DNA-PK does not regulate the differentiation program itself.
Thus, clues to understanding the mechanisms driving WM biology may lie within this lymphoplasmacytic differentiation process itself.
It is likely that these proteins play a role in the differentiation process itself and may therefore provide a potential therapeutic target in the treatment of neuroblastoma.
