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With regard to genes differentially expressed in the basal compartment, our results indicate that normal myoepithelial differentiation is associated with the block of cell progression at the G1 phase of the cell cycle, as suggested by the down-regulation of CCNE1.
Cellular differentiation is associated with dynamic chromatin remodeling in establishing a cell-type-specific epigenomic landscape.
These findings indicate that the decrease in redox ratio during adipogenic differentiation is associated with fatty acid synthesis and lipid accumulation.
Cell differentiation is associated with progressive immobilization of chromatin proteins, expansion of heterochromatin, decrease of global transcriptional activity and induction of lineage-specific genes.
To determine if very early serum hCG, a marker of trophoblast differentiation, is associated with adverse perinatal outcomes in singleton pregnancies.
We conclude that butyrate-induced differentiation is associated with specific and localized changes in the histone acetylation state within the IAP promoter.
BrdU staining results showed that the population of proliferating cells decreased in miR-124a-treated F11 cells suggesting that miR-124a-induced neuronal differentiation is associated with the decreased proliferation.
LSC differentiation is associated with reversal of these broad epigenetic profiles, with concomitant downregulation of crucial MLL target genes and the LSC maintenance transcriptional program that is driven by the loss of H3K4me3, but not H3K79me2.
Bone marrow derived human mesenchymal stem cells (hMSC) are the primary cell type in bone tissue engineering, and their life span during osteogenic differentiation is associated with changes in oxygen tension.
Adipocyte differentiation is associated with mitochondrial biogenesis [55].
Previously, we demonstrated that intestinal cell differentiation is associated with the induction of TRAIL expression [10].
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